The Biofluids Control Systems Course provides education and research from the standpoints of both fluid dynamics and biology, aimed at clarifying the mechanisms of circulatory system diseases and establishing methods for treatment and prevention, based on an understanding of the blood circulating system and other complex fluid systems in the body. We teach the following fields.
Integrated Biomedical Simulation
Integration of measurement and simulation to comprehend complex biofluid phenomena
The Integrated Biomedical Simulation Laboratory conducts education and research for understanding complex biofluid phenomena and development of advanced medical technologies through experimental work utilizing ultrasound, laser, image processing; numerical work using a supercomputer, and the work combining experimental and numerical methodologies. Main research projects are listed below.
- Measurement-integrated blood flow simulation
- Mechanical properties of cells with inclined-centrifuge microscope
- Dynamics of biofluid systems
- Microfluidic device mimicking in vivo microenvironment
Cellular experiment using microfluidic device
Biomedical Fluid System
To approach the structures and function of the body through biomedical engineering.
The focus of this laboratory is to develop new concept of implant especially based on flow and to establish new methods for evaluating the implants. For example, when you treat a cerebral aneurysm with endovascular treatment, you should know the effects of medical devices on controls of blood flow. The flow may depend on the geometry, materials and clinical conditions. Since these are so big issues, we collaborate with biomaterial groups, biomechanical groups, and medical groups to gather their top knowledge.
- The development of blood vessel, oral mucosa, and bone biomodels using biomaterial gel
- Computational simulation for blood flow in aneurysms with treatments
- Development of in-situ measurement of blood flow in treatments
Development of cerebral aneurysm model with realistic physical material properties.
Blood flow in stent on cerebral artery with aneurysm