Biofluids Control System

The Biofluids Control Systems Course provides education and research from the standpoints of both fluid dynamics and biology, aimed at clarifying the mechanisms of circulatory system diseases and establishing methods for treatment and prevention, based on an understanding of the blood circulating system and other complex fluid systems in the body. We teach the following fields.

Integrated Biomedical Simulation

Creation of technology for reproduction of in vivo microenvironment and control of cell dynamics

  • Associate Professor Kenichi Funamoto Associate Professor
    Kenichi Funamoto

For technical innovation of treatment and prevention for diseases, it is essential to elucidate mechanisms of homeostasis and in vivo phenomena involved in development and progression of the diseases. We are investigating individual cell responses to spatiotemporal variations of microenvironment, as well as cell-cell and cell-extracellular matrix interactions, and conducting research to operate them. Through research activity by integrating biomedical engineering and cell biology based on fluid engineering, a good grounding to conduct interdisciplinary research will be developed.

  1. Development of microfluidic devices to reproduce in vivo microenvironments.
  2. Analysis and control of cellular dynamics in response to environmental factors.
  3. Elucidation of biofunctions by measurement-integrated simulation and their medical applications.
A microfluidic device to mimic in vivo microenvironment, and a microscopic image of microvascular network created inside the device.

A microfluidic device to mimic in vivo microenvironment, and a microscopic image of microvascular network created inside the device.

Biomedical Fluid System

To approach the structures and function of the body through biomedical engineering.

  • Professor Makoto Ohta Professor
    Makoto Ohta

The focus of this laboratory is to develop new concept of implant especially based on flow and to establish new methods for evaluating the implants. For example, when you treat a cerebral aneurysm with endovascular treatment, you should know the effects of medical devices on controls of blood flow. The flow may depend on the geometry, materials and clinical conditions. Since these are so big issues, we collaborate with biomaterial groups, biomechanical groups, and medical groups to gather their top knowledge.

  1. The development of blood vessel, oral mucosa, and bone biomodels using biomaterial gel
  2. Computational simulation for blood flow in aneurysms with treatments
  3. Development of in-situ measurement of blood flow in treatments
  • Development of cerebral aneurysm model with realistic physical material properties.

    Development of cerebral aneurysm model with realistic physical material properties.

  • Blood flow in stent on cerebral artery with aneurysm

    Blood flow in stent on cerebral artery with aneurysm

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