Biofluids Control System

The Biofluids Control Systems Course provides education and research from the standpoints of both fluid dynamics and biology, aimed at clarifying the mechanisms of circulatory system diseases and establishing methods for treatment and prevention, based on an understanding of the blood circulating system and other complex fluid systems in the body. We teach the following fields.

Integrated Biomedical Simulation

Creation of technology for reproduction of in vivo microenvironment and control of cell dynamics

  • Professor Kenichi Funamoto Professor
    Kenichi Funamoto

For technical innovation of treatment and prevention for diseases, it is essential to elucidate mechanisms of homeostasis and in vivo phenomena involved in development and progression of the diseases. We are investigating individual cell responses to spatiotemporal variations of microenvironment, as well as cell-cell and cell-extracellular matrix interactions, and conducting research to operate them. Through research activity by integrating biomedical engineering and cell biology based on fluid engineering, a good grounding to conduct interdisciplinary research will be developed.

  1. Development of microfluidic devices to reproduce in vivo microenvironments.
  2. Analysis and control of cellular dynamics in response to environmental factors.
  3. Elucidation of biofunctions by measurement-integrated simulation and their medical applications.
A microfluidic device to mimic in vivo microenvironment, and a microscopic image of microvascular network created inside the device.

A microfluidic device to mimic in vivo microenvironment, and a microscopic image of microvascular network created inside the device.

Biomedical Fluid System

To approach the structures and function of the body through biomedical engineering.

  • Professor Makoto Ohta Professor
    Makoto Ohta
  • Associate Professor Hitomi Anzai Associate Professor
    Hitomi Anzai

Our aim is to develop new devices that directly contribute to treatment and to establish methods for evaluating their performance. Through these activities, we can gain a deeper understanding of the structure and function of biology. In particular, we believe that blood flow and blood walls are the most critical elements for sustaining life, and so we conduct research on the detection, diagnosis, and treatment of cerebral aneurysms. Specifically, we reproduce biological and mechanical environments and structures by using experimental and computational simulations.
We engage international collaboration and focusing our efforts on the following areas:

  1. Development of vascular models replicating the mechanical environment of living organs.
  2. Computational fluid dynamics of blood flow with medical devices.
  3. Development of ultra-high-speed blood flow prediction using AI.
  4. Analysis of cell responses to blood flow with biomaterials.
  • AI-based prediction of blood flow

    AI-based prediction of blood flow

  • Promotion of Medical Science Committee, Tohoku University
  • ALicE:Association of Leading Women Researchers in School of Engineering, Tohoku University
  • Connect Engineering